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1) Ethambutol inhibits arabinosyl transferase III, disrupting the transfer of arabinose into arabinogalactan biosynthesis and cell wall assembly. 2) Isoniazid is activated by KatG into its toxic form, which interacts with mycobacterial NAD and NADP to inhibit enzymes involved in mycolic acid and nucleic acid synthesis, killing the bacteria. 3) Both drugs are used to treat tuberculosis and related infections. Common adverse effects include optic neuritis, hepatitis, and peripheral neuropathy. Drug interact

Author

Johara

Language

EN