Opening book details…
Can I read Early hypophosphatemia in critically ill children and the effect of parenteral nutrition: A secondary analysis of the PEPaNIC RCT on EtoBox?
Early hypophosphatemia in critically ill children and the effect of parenteral nutrition: A secondary analysis of the PEPaNIC RCT by K. Veldscholte; M.A.N. Veen; R.D. Eveleens; R.C.J. de Jonge; I. Vanhorebeek; J. Gunst; M.P. Casaer; P.J. Wouters; Gonzalo Garcia Guerra; G. Van den Berghe; K.F.M. Joosten; S.C.A.T. Verbruggen is a Medicine article available to read on EtoBox.
What is Early hypophosphatemia in critically ill children and the effect of parenteral nutrition: A secondary analysis of the PEPaNIC RCT about?
## Background & aims: Hypophosphatemia during critical illness has been associated with adverse outcome. the reintroduction of enteral or parenteral nutrition, leading to refeeding hypophosphatemia (rfh), has been presented as potential risk factor. we investigated the occurrence of early rfh, its association with clinical outcome, and the impact of early parenteral nutrition (pn) on the development of early rfh in pediatric critical illness. ## Methods: This is a secondary analysis of the pepanic randomized controlled trial (n = 1440), which showed that withholding supplemental parenteral nutrition (pn) for 1 week (late-pn) in the pediatric intensive care unit (picu) accelerated recovery and reduced new infections compared to early-pn (<24 h). patients with renal replacement therapy or unavailable phosphate concentrations were excluded from this analysis. early rfh was defined as serum/plasma phosphate 0.16 mmol/l within 3 days of admission to the picu. the association between baseline characteristics and early rfh, and the association of early rfh with clinical outcome were investigated using logistic and linear regression models, both uncorrected and corrected for possible conf
Who reads Early hypophosphatemia in critically ill children and the effect of parenteral nutrition: A secondary analysis of the PEPaNIC RCT?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- K. Veldscholte; M.A.N. Veen; R.D. Eveleens; R.C.J. de Jonge; I. Vanhorebeek; J. Gunst; M.P. Casaer; P.J. Wouters; Gonzalo Garcia Guerra; G. Van den Berghe; K.F.M. Joosten; S.C.A.T. Verbruggen
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)