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Synthetic Cages Associated With Increased Rates of Revision Surgery and Higher Costs Compared to Allograft in ACDF in the Nonelderly Patient by Majd Marrache; Rachel Bronheim; Andrew B. Harris; Varun Puvanesarajah; Micheal Raad; Sang Lee; Richard Skolasky; Amit Jain is a Medicine article available to read on EtoBox.

What is Synthetic Cages Associated With Increased Rates of Revision Surgery and Higher Costs Compared to Allograft in ACDF in the Nonelderly Patient about?

## Objective The aim of this study was to compare all-cause reoperation rates and costs in nonelderly patients treated with anterior cervical discectomy and fusion (ACDF) with structural allograft versus synthetic cages for degenerative pathology. ## Methods We queried a private claims database to identify adult patients (≤ 65 years) who underwent single-level ACDF in a hospital setting using either structural allograft or a synthetic cage (polyetheretherketone, metal, or hybrid device), from 2010 to 2016. The rate of all-cause reoperations at 2 years were compared between the 2 groups. Index hospitalization costs and 90-day complication rates were also compared. Significance was set at p < 0.05. ## Results A total of 26,754 patients were included in the study. 11,514 patients (43%) underwent ACDF with structural allograft and 15,240 (57%) underwent ACDF with a synthetic cage. The patients in the allograft group were younger and more likely to be male. There was no significant difference between the 2 groups with respect to 90-day complications including: wound dehiscence, dysphagia, dysphonia, and hematoma/seroma. In the 2-year postoperative period, the synthetic cage group had a

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Author
Majd Marrache; Rachel Bronheim; Andrew B. Harris; Varun Puvanesarajah; Micheal Raad; Sang Lee; Richard Skolasky; Amit Jain
Publisher
The Korean Spinal Neurosurgery Society
Published
2020
Language
EN
Field
Medicine (Health Sciences)

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