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Preclinical development involves laboratory research on potential new drugs and medical devices before human testing. This stage determines a safe starting dose for clinical trials and assesses toxicity through tests on animals. On average, only one in 5,000 compounds makes it through preclinical development to become an approved drug. Tests examine pharmacokinetics, dynamics, and toxicity, providing data to estimate a safe human starting dose. Both in vitro and in vivo animal tests are typically conducted

Author

Mukta fule

Language

EN