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Association of Perioperative Red Blood Cell Transfusions With Venous Thromboembolism in a North American Registry by Ruchika Goel; Eshan U. Patel; Melissa M. Cushing; Steven M. Frank; Paul M. Ness; Clifford M. Takemoto; Ljiljana V. Vasovic; Sujit Sheth; Marianne E. Nellis; Beth Shaz; Aaron A. R. Tobian is a Medicine article available to read on EtoBox.

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## Importance: Increasing evidence supports the role of red blood cells (rbcs) in physiological hemostasis and pathologic thrombosis. red blood cells are commonly transfused in the perioperative period; however, their association with postoperative thrombotic events remains unclear. ## Objective: To examine the association between perioperative rbc transfusions and postoperative venous thromboembolism (vte) within 30 days of surgery. ## Design, setting, and participants: This analysis used prospectively collected registry data from the american college of surgery national surgical quality improvement program (acs-nsqip) database, a validated registry of 525 teaching and nonteaching hospitals in north america. participants included patients in the acs-nsqip registry who underwent a surgical procedure from january 1 through december 31, 2014. data were analyzed from july 1, 2016, through march 15, 2018. ## Main outcomes and measures: Risk-adjusted odds ratios (aors) were estimated using multivariable logistic regression. the primary outcome was the development of postoperative vte (deep venous thrombosis [dvt] and pulmonary embolism [pe]) within 30 days of surgery that warranted ther

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Author

Ruchika Goel; Eshan U. Patel; Melissa M. Cushing; Steven M. Frank; Paul M. Ness; Clifford M. Takemoto; Ljiljana V. Vasovic; Sujit Sheth; Marianne E. Nellis; Beth Shaz; Aaron A. R. Tobian

Published

2018

Language

EN

Field

Medicine (Health Sciences)