Can I read Cannabis Use and Sensorimotor Gating in Patients with Schizophrenia and Healthy Controls on EtoBox?

Cannabis Use and Sensorimotor Gating in Patients with Schizophrenia and Healthy Controls by Kirsty E. Scholes-Balog; Mathew T. Martin-Iverson is a Medicine article available to read on EtoBox.

What is Cannabis Use and Sensorimotor Gating in Patients with Schizophrenia and Healthy Controls about?

## Objective Schizophrenia patients and healthy cannabis users show different attention‐dependant alterations in prepulse inhibition (PPI). It is of interest then to examine PPI in patients with schizophrenia who use cannabis, given the hypothesized association between cannabis use and schizophrenia. ## Methods Prepulse inhibition was measured in 34 healthy cannabis users, 32 healthy non‐using controls, 20 patients with schizophrenia who were current cannabis users, and 44 non‐using patients with schizophrenia. PPI was measured across a range of startling stimulus intensities, during two attention set conditions. Curves of best fit were fitted to the startle magnitudes, across the stimulus intensities. A number of reflex parameters were extracted from these logistic functions. ## Results Similar to healthy cannabis users, cannabis‐using patients showed altered PPI of __Threshold__, only when instructed to sustain attention to the auditory stimuli. Conversely, non‐using patients with schizophrenia showed reduced PP of __R__~MAX~ only when instructed to ignore the auditory stimuli. ## Conclusion Cannabis use in patients with schizophrenia is associated with a similar pattern of atten

Who reads Cannabis Use and Sensorimotor Gating in Patients with Schizophrenia and Healthy Controls?

Author

Kirsty E. Scholes-Balog; Mathew T. Martin-Iverson

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0885-6222)

Published

2011

Language

EN

Field

Medicine (Health Sciences)