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Dietary fat intake and the risk of incident dementia in the Rotterdam Study by Dr. Sandra Kalmijn; Lenore J. Launer; Alewijn Ott; Jacqueline C. M. Witteman; Albert Hofman; Monique M. B. Breteler is a Medicine article available to read on EtoBox.

What is Dietary fat intake and the risk of incident dementia in the Rotterdam Study about?

A high intake of saturated fat and cholesterol and a low intake of polyunsaturated fatty acids have been related to an increased risk of cardiovascular disease. Cardiovascular disease has been associated with dementia. We investigated the association between fat intake and incident dementia among participants, age 55 years or older, from the population-based prospective Rotterdam Study. Food intake of 5,386 nondemented participants was assessed at baseline with a semiquantitative food-frequency questionnaire. At baseline and after an average of 2.1 years of follow-up, we screened for dementia with a three-step protocol that included a clinical examination. The risk of dementia at follow-up (RR [95% CI]) was assessed with logistic regression. After adjustment for age, sex, education, and energy intake, high intakes of the following nutrients were associated with an increased risk of dementia: total fat (RR = 2.4 [1.1-5.2]), saturated fat (RR = 1.9 [0.9-4.0]), and cholesterol (RR = 1.7 [0.9-3.2]). Dementia with a vascular component was most strongly related to total fat and saturated fat. Fish consumption, an important source of n-3 polyunsaturated fatty acids, was inversely related

Who reads Dietary fat intake and the risk of incident dementia in the Rotterdam Study?

Author

Dr. Sandra Kalmijn; Lenore J. Launer; Alewijn Ott; Jacqueline C. M. Witteman; Albert Hofman; Monique M. B. Breteler

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0364-5134)

Published

1997

Language

EN

Field

Medicine (Health Sciences)