Opening book details…
Can I read Bioavailability of Single-Dose SUBA-Itraconazole Compared to Conventional Itraconazole under Fasted and Fed Conditions on EtoBox?
Bioavailability of Single-Dose SUBA-Itraconazole Compared to Conventional Itraconazole under Fasted and Fed Conditions by Adriana M. Rauseo; Patrick Mazi; Phoebe Lewis; Bruce Burnett; Stuart Mudge; Andrej Spec is a Medicine article available to read on EtoBox.
What is Bioavailability of Single-Dose SUBA-Itraconazole Compared to Conventional Itraconazole under Fasted and Fed Conditions about?
Conventional itraconazole (C-ITZ) suffers from absorption variability. SUBA-itraconazole (S-ITZ) is more bioavailable than C-ITZ at steady state in a fed condition, but there are no data comparing the two under a fasted state. An open-label, single-dose, randomized, bioequivalence study was performed comparing S-ITZ to C-ITZ capsules under fasted and fed conditions in healthy adults measuring itraconazole and hydroxyitraconazole plasma levels. This study demonstrated less variability of S-ITZ compared to C-ITZ capsules under fasted conditions.
Who reads Bioavailability of Single-Dose SUBA-Itraconazole Compared to Conventional Itraconazole under Fasted and Fed Conditions?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Adriana M. Rauseo; Patrick Mazi; Phoebe Lewis; Bruce Burnett; Stuart Mudge; Andrej Spec
- Publisher
- American Society for Microbiology
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)