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Respiratory muscle dysfunction in long-COVID patients by Jan K. Hennigs; Marie Huwe; Annette Hennigs; Tim Oqueka; Marcel Simon; Lars Harbaum; Jakob Körbelin; Stefan Schmiedel; Julian Schulze zur Wiesch; Marylyn M. Addo; Stefan Kluge; Hans Klose is a Medicine article available to read on EtoBox.

What is Respiratory muscle dysfunction in long-COVID patients about?

## Abstract ## Purpose Symptoms often persistent for more than 4 weeks after COVID-19—now commonly referred to as ‘Long COVID’. Independent of initial disease severity or pathological pulmonary functions tests, fatigue, exertional intolerance and dyspnea are among the most common COVID-19 sequelae. We hypothesized that respiratory muscle dysfunction might be prevalent in persistently symptomatic patients after COVID-19 with self-reported exercise intolerance. ## Methods In a small cross-sectional pilot study (n = 67) of mild-to-moderate (nonhospitalized) and moderate-to-critical convalescent (formerly hospitalized) patients presenting to our outpatient clinic approx. 5 months after acute infection, we measured neuroventilatory activity P~0.1~, inspiratory muscle strength (PI~max~) and total respiratory muscle strain (P~0.1~/PI~max~) in addition to standard pulmonary functions tests, capillary blood gas analysis, 6 min walking tests and functional questionnaires. ## Results Pathological P~0.1~/PI~max~ was found in 88% of symptomatic patients. Mean PI~max~ was reduced in hospitalized patients, but reduced PI~max~ was also found in 65% of nonhospitalized patients. Mean P~0.1~ was path

Who reads Respiratory muscle dysfunction in long-COVID patients?

Author

Jan K. Hennigs; Marie Huwe; Annette Hennigs; Tim Oqueka; Marcel Simon; Lars Harbaum; Jakob Körbelin; Stefan Schmiedel; Julian Schulze zur Wiesch; Marylyn M. Addo; Stefan Kluge; Hans Klose

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)