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Can I read Development of the Bleeding and Pelvic Discomfort Scale for Use in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids on EtoBox?
Development of the Bleeding and Pelvic Discomfort Scale for Use in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids by Stacie Hudgens; Martha Gauthier; Elke Hunsche; Jennifer Kang; Yulan Li; Kayla Scippa; Sawsan As-Sanie is a Economics, Econometrics and Finance article available to read on EtoBox.
What is Development of the Bleeding and Pelvic Discomfort Scale for Use in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids about?
## Objectives: This study aimed to define a cardinal symptom burden measure based on items from the uterine fibroid symptom and quality of life questionnaire for use as a clinical trial endpoint. ## Methods: Exploratory factor analysis was computed to assess the uterine fibroid symptom and quality of life symptom severity scale factor structure, using phase 2 data. pooled blinded data from phase 3 studies were used for the confirmatory factor analysis and the psychometric evaluation of the new measure. exit interviews in 30 patients from phase 3 studies provided additional qualitative evidence. a meaningful change threshold was determined using anchor-based analyses supported by patient feedback in the exit interviews. ## Results: Three factors emerged from the exploratory factor analysis. factor 1, called the bleeding and pelvic discomfort (bpd) scale, consists of cardinal symptoms, measuring menstrual distress owing to heavy bleeding, passing blood clots, and feeling tightness or pressure in pelvic area. patients generally understood the items in the scale and the recall period as intended. the bpd scale had good item performance and internal consistency reliability, strong item-
Who reads Development of the Bleeding and Pelvic Discomfort Scale for Use in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids?
It is typically read by researchers, students, and practitioners in Economics, Econometrics and Finance.
- Author
- Stacie Hudgens; Martha Gauthier; Elke Hunsche; Jennifer Kang; Yulan Li; Kayla Scippa; Sawsan As-Sanie
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Economics, Econometrics and Finance (Social Sciences)