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Perspectives on Transcriptomics in Animal Physiology Studies by Christopher J. Martyniuk is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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Reductionist approaches in physiology and biochemistry are essential for understanding how animals cope and adapt to their environments. Transcriptomics is no longer restricted to a select few, and accessibility and affordability continue to facilitate its rapid growth as a science. More than 6000 publications (a conservative estimate) over the past decade quantify the response of the transcriptome to a wide breadth of questions in animal physiology. Transcriptomes have been quantified under conditions of hypoxia, climate change, salinity, drought, environmental pollution, and ultraviolet radiation among others; these studies have greatly improved understanding of the molecular machinery required for organismal adaptation. These "snapshots in time" however are never complete as the transcriptome is exquisitely sensitive to an individual's current physiologic state. Animal physiologists new to the field must recognize limitations of transcriptome technologies and consider experimental designs that strengthen physiologic interpretation. Current estimates suggest that a sample size of 6 or more are required for RNA-seq experiments in order to capture the majority of differentially exp

Who reads Perspectives on Transcriptomics in Animal Physiology Studies?

Author

Christopher J. Martyniuk

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 1096-4959)

Published

2020

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)