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The Impact of COVID-19 on the Profile of Hospital-Acquired Infections in Adult Intensive Care Units by Despotovic, Aleksa (author);Milosevic, Branko (author);Cirkovic, Andja (author);Vujovic, Ankica (author);Cucanic, Ksenija (author);Cucanic, Teodora (author);Stevanovic, Goran (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is The Impact of COVID-19 on the Profile of Hospital-Acquired Infections in Adult Intensive Care Units about?

Hospital-acquired infections (HAIs) are a global public health concern. As the COVID-19 pandemic continues, its contribution to mortality and antimicrobial resistance (AMR) grows, particularly in intensive care units (ICUs). A two-year retrospective study from April 2019–April 2021 was conducted in an adult ICU at the Hospital for Infectious and Tropical Diseases, Belgrade, Serbia to assess causative agents of HAIs and AMR rates, with the COVID-19 pandemic ensuing halfway through the study. Resistance rates >80% were observed for the majority of tested antimicrobials. In COVID-19 patients, Acinetobacter spp. was the dominant cause of HAIs and more frequently isolated than in non-COVID-19 patients. (67 vs. 18, p = 0.001). Also, resistance was higher for imipenem (56.8% vs. 24.5%, p < 0.001), meropenem (61.1% vs. 24.3%, p < 0.001) and ciprofloxacin (59.5% vs. 36.9%, p = 0.04). AMR rates were aggregated with findings from our previous study to identify resistance trends and establish empiric treatment recommendations. The increased presence of Acinetobacter spp. and a positive trend in Klebsiella spp. resistance to fluoroquinolones (R2 = 0.980, p = 0.01) and carbapenems (R2 = 0.963, p

Who reads The Impact of COVID-19 on the Profile of Hospital-Acquired Infections in Adult Intensive Care Units?

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
Despotovic, Aleksa (author);Milosevic, Branko (author);Cirkovic, Andja (author);Vujovic, Ankica (author);Cucanic, Ksenija (author);Cucanic, Teodora (author);Stevanovic, Goran (author)
Publisher
MDPI AG
Published
2021
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)

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