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Drug metabolism concepts : a symposium cosponsored by the Division of Medicinal Chemistry and the division of Analytical Chemistry at the 172nd meeting of the American Chemical Society, San Francisco, Calif., August 31, 1976 by DONALD M. JERINA; R. W. ESTABROOK; J. WERRINGLOER; JAMES P. COLLMAN; THOMAS N. SORRELL; M. J. COON; J. L. VERMILION; K. P. VATSIS; J. S. FRENCH; W. L. DEAN; D. A. HAUGEN; ERIC F. JOHNSON; URSULA MULLER-EBERHARD; WILLIAM F. TRAGER; W. LEVIN; A. W. WOOD; A. Y. H. LU; D. RYAN; S. WEST; A. H. CONNEY; D. R. THAKKER; H. YAGI; D. M. JERINA; P. D. MOORE; M. KOREEDA; P. G. WISLOCKI; SIDNEY D. NELSON; MICHAEL R. BOYD; JERRY R. MITCHELL is a book available to read on EtoBox.

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ix, 196 pages : 24 cm Includes bibliographical references and index Cytochrome P-450 : its role in oxygen activation for drug metabolism / R.W. Estabrook and J. Werringloer -- Synthetic models for the reaction stages of cytochrome P-450 / James P. Collman and Thomas N. Sorrell -- Biochemical studies on drug metabolism : isolation of multiple forms of liver microsomal cytochrome P-450 / M.J. Coon, J.L. Vermilion, K.P. Vatsis, J.S. French, W.L. Dean, and D.A. Haugen -- Resolution of multiple forms of rabbit liver cytochrome P-450 / Eric F. Johnson and Ursula Muller-Eberhard -- Enantiomeric selectivity and perturbation of product ratios as methods for studying the multiplicity of microsomal enzymes / William F. Trager -- Role of purified cytochrome P-448 and epoxide hydrase in the activation and detoxification of benzo[a]pyrene / W. Levin, A.W. Wood, A.Y.H. Lu, D. Ryan, S. West, A.H. Conney, D.R. Thakker, H. Yagi, and D.M. Jerina -- In vitro reactions of the diastereomeric 9,10-epoxides of (+) and ( -- )-trans-7,8-dihydroxy-7,8-dihydrobenzo-[a]pyrene with polyguanylic acid and evidence for formation of an enantiomer of each diastereomeric 9,10-epoxide from benzo[a]pyrene in mouse skin

Author

DONALD M. JERINA; R. W. ESTABROOK; J. WERRINGLOER; JAMES P. COLLMAN; THOMAS N. SORRELL; M. J. COON; J. L. VERMILION; K. P. VATSIS; J. S. FRENCH; W. L. DEAN; D. A. HAUGEN; ERIC F. JOHNSON; URSULA MULLER-EBERHARD; WILLIAM F. TRAGER; W. LEVIN; A. W. WOOD; A. Y. H. LU; D. RYAN; S. WEST; A. H. CONNEY; D. R. THAKKER; H. YAGI; D. M. JERINA; P. D. MOORE; M. KOREEDA; P. G. WISLOCKI; SIDNEY D. NELSON; MICHAEL R. BOYD; JERRY R. MITCHELL

Publisher

Washington: American Chemical Society

Published

1977

Language

EN

ISBN

9780841203549

Subjects

Medical, Medicine