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Comprehensive AML Diagnostics via RNA Sequencing by udeshmadhushanka9 is a document available to read on EtoBox.
This study presents HAMLET, a comprehensive bioinformatics pipeline for diagnosing acute myeloid leukemia (AML) using whole transcriptome RNA sequencing. HAMLET enables simultaneous detection of fusion genes, small variants, and gene expression, achieving high sensitivity and specificity in identifying genetic aberrations relevant for AML classification and targeted therapy. The results indicate that HAMLET can streamline AML diagnostics, potentially improving patient outcomes through more accurate risk ass
- Author
- udeshmadhushanka9
- Language
- EN