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Is 12 Systemic Cores in Transperineal Biopsy Sufficient for Detecting Clinically Significant Prostate Cancer? by S.A. Rhew; C.E. Yoon; H.J. Kwon; D.H Shin; H.W. Moon; Y.H. Park; W.J. Bae; H.J. Cho; U.S Ha; S.H Hong; J.Y. Lee; S.W. Kim is a Medicine article available to read on EtoBox.
What is Is 12 Systemic Cores in Transperineal Biopsy Sufficient for Detecting Clinically Significant Prostate Cancer? about?
Introduction & Objectives: Recently, for histologic diagnosis of prostate cancer, transperineal (TP) biopsy shows superior cancer detection rate than transrectal biopsy and is recommended due to low risk of infection. The target biopsy for visible lesion on MRI is essential, but the systemic biopsy is also important for detection of non-visible lesion on MRI. However, there is no consensus of the number of systemic core. This study aims to confirm the diagnostic efficiency of 20-core systemic biopsy by comparison with 12-core systemic biopsy using propensity score matching. ## Materials & Methods: The 494 patients who were conducted the naive TP biopsy from February 2021 to May 2022, were retrospectively analyzed. There were 293 patients with 12-core biopsy and 201 patients with 20-core biopsy. Propensity score matching analysis was performed for minimizing confounding variables, and the established effects value was analyzed for clinically significant prostate cancer (csPCa) and 'index negative' csPCa. ## Results: At 12-core biopsy, there were 126 cases of prostate cancer (43.0%), and 97 cases of csPCa (33.1%). At 20-core biopsy, there were 91 cases of prostate cancers (45.3%) and
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- Author
- S.A. Rhew; C.E. Yoon; H.J. Kwon; D.H Shin; H.W. Moon; Y.H. Park; W.J. Bae; H.J. Cho; U.S Ha; S.H Hong; J.Y. Lee; S.W. Kim
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)