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Treatment with Inhaled Corticosteroids in Asthma Is Too Often Discontinued by Nancy S. Breekveldt‐Postma; Jeroen Koerselman; Joëlle A. Erkens; Thys van der Molen; Jan‐Willem J. Lammers; Ron M. C. Herings; for the CAMERA Study Group is a Medicine article available to read on EtoBox.
What is Treatment with Inhaled Corticosteroids in Asthma Is Too Often Discontinued about?
## Abstract ## Purpose To study persistence with inhaled corticosteroids (ICS) and its determinants in asthma‐patients. ## Methods From the PHARMO database, asthma‐patients (age < 35 years) with a first dispensing for ICS in 1999–2002 and ≥ 2 dispensings in the first year were included. Persistence during the first year was defined as the number of days from start to time of first failure to continue renewal of the initial ICS. Potential determinants of persistence were assessed at ICS‐start and 1 year before. ## Results The study‐cohort included 5563 new users of single ICS and 297 of fixed‐combined ICS. Less than 10% of patients using single ICS and 15% of patients using fixed‐combined ICS were persistent at 1 year. Similar persistence‐rates were observed when stratified for age (children/adolescents: 0–18 years and adults: 19–34 years). Increased persistence with single ICS was observed with the type of ICS (budesonide), prescriber (specialist), prior use of long‐acting beta‐agonists, previous hospitalization for asthma, metered‐dose inhaler, low starting‐dose and once‐daily dosing regimen at start. Persistence with fixed combined ICS‐treatment increased with younger age and was
Who reads Treatment with Inhaled Corticosteroids in Asthma Is Too Often Discontinued?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Nancy S. Breekveldt‐Postma; Jeroen Koerselman; Joëlle A. Erkens; Thys van der Molen; Jan‐Willem J. Lammers; Ron M. C. Herings; for the CAMERA Study Group
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-8569)
- Published
- 2008
- Language
- EN
- Field
- Medicine (Health Sciences)