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What is Gluconeogenesis Pathway Explained about?

Gluconeogenesis is the synthesis of glucose from non-carbohydrate precursors like lactate or amino acids. It occurs primarily in the liver. The pathway broadly follows glycolysis in reverse, with three exceptions. Pyruvate is converted to phosphoenolpyruvate using two ATP in a two step process involving pyruvate carboxylase and PEP carboxykinase. Fructose-1,6-bisphosphatase and glucose-6-phosphatase bypass other normally irreversible steps. Overall, gluconeogenesis requires 4-6 ATP equivalents to synthesize

Author

harshit

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EN