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Bretylium tosylate is an antiarrhythmic agent that causes a chemical sympathectomy-like state by inhibiting norepinephrine release and depressing adrenergic nerve terminal excitability. It has a half-life of about 7.8 hours and is eliminated intact by the kidneys. Bretylium tosylate is indicated for the prophylaxis and treatment of ventricular fibrillation and life-threatening ventricular arrhythmias that have failed to respond to first-line antiarrhythmic agents. Common adverse reactions include orthostati

Author

Butchay Lumbab

Language

EN