Can I read Functional Therapies for Cutaneous Wound Repair in Epidermolysis Bullosa on EtoBox?

Functional Therapies for Cutaneous Wound Repair in Epidermolysis Bullosa by Patricia Peking; Ulrich Koller; Eva M. Murauer is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Functional Therapies for Cutaneous Wound Repair in Epidermolysis Bullosa about?

Chronic wounding as a result of recurrent skin blistering in the painful genetic skin disease epidermolysis bullosa, may lead to life-threatening infections, increased risk of tumor formation, and other serious medical complications. Therefore, epidermolysis bullosa patients have an urgent need for optimal wound care and tissue regeneration. Therapeutic strategies using gene-, protein-, and cell-therapies are being developed to improve clinical symptoms, and some of them have already been investigated in early clinical trials. The most favorable options of functional therapies include gene replacement, gene editing, RNA targeting, and harnessing natural gene therapy. This review describes the current progress of the different approaches targeting autologous skin cells, and will discuss the benefits and challenges of their application.

Who reads Functional Therapies for Cutaneous Wound Repair in Epidermolysis Bullosa?

Author

Patricia Peking; Ulrich Koller; Eva M. Murauer

Published

2017

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)