Can I read At what costs will screening with CT colonography be competitive? A cost‐effectiveness approach on EtoBox?

At what costs will screening with CT colonography be competitive? A cost‐effectiveness approach by Iris Lansdorp‐Vogelaar; Marjolein van Ballegooijen; Ann G. Zauber; Rob Boer; Janneke Wilschut; J. Dik F. Habbema is a Medicine article available to read on EtoBox.

What is At what costs will screening with CT colonography be competitive? A cost‐effectiveness approach about?

## Abstract The costs of computed tomographic colonography (CTC) are not yet established for screening use. In our study, we estimated the threshold costs for which CTC screening would be a cost‐effective alternative to colonoscopy for colorectal cancer (CRC) screening in the general population. We used the MISCAN‐colon microsimulation model to estimate the costs and life‐years gained of screening persons aged 50–80 years for 4 screening strategies: (__i__) optical colonoscopy; and CTC with referral to optical colonoscopy of (__ii__) any suspected polyp; (__iii__) a suspected polyp ≥6 mm and (__iv__) a suspected polyp ≥10 mm. For each of the 4 strategies, screen intervals of 5, 10, 15 and 20 years were considered. Subsequently, for each CTC strategy and interval, the threshold costs of CTC were calculated. We performed a sensitivity analysis to assess the effect of uncertain model parameters on the threshold costs. With equal costs ($662), optical colonoscopy dominated CTC screening. For CTC to gain similar life‐years as colonoscopy screening every 10 years, it should be offered every 5 years with referral of polyps ≥6 mm. For this strategy to be as cost‐effective as colonoscopy sc

Who reads At what costs will screening with CT colonography be competitive? A cost‐effectiveness approach?

Author

Iris Lansdorp‐Vogelaar; Marjolein van Ballegooijen; Ann G. Zauber; Rob Boer; Janneke Wilschut; J. Dik F. Habbema

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)

Published

2008

Language

EN

Field

Medicine (Health Sciences)