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This study investigates the in vivo effects of glucocorticoids, specifically prednisone, on IgE production in asthma patients. After a 7-day course of prednisone, all 10 patients exhibited a significant increase in serum IgE levels, while also showing improved pulmonary function, suggesting that the rise in IgE is not clinically harmful. The findings indicate that corticosteroids may have immunomodulatory effects on T lymphocytes without adversely affecting asthma control.

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rahul.2405886104

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EN