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Do Changes in Traditional Coronary Heart Disease Risk Factors Over Time Explain the Association Between Socio-economic Status and Coronary Heart Disease? by Peter Franks; Paul C Winters; Daniel J Tancredi; Kevin A Fiscella is a Medicine article available to read on EtoBox.

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## Background Socioeconomic status (SES) predicts coronary heart disease independently of the traditional risk factors included in the Framingham risk score. However, it is unknown whether __changes__ in Framingham risk score variables over time explain the association between SES and coronary heart disease. We examined this question given its relevance to risk assessment in clinical decision making. ## Methods The Atherosclerosis Risk in Communities study data (initiated in 1987 with 10-years follow-up of 15,495 adults aged 45-64 years in four Southern and Mid-Western communities) were used. SES was assessed at baseline, dichotomized as low SES (defined as low education and/or low income) or not. The time dependent variables - smoking, total and high density lipoprotein cholesterol, systolic blood pressure and use of blood pressure lowering medication - were assessed every three years. Ten-year incidence of coronary heart disease was based on EKG and cardiac enzyme criteria, or adjudicated death certificate data. Cox survival analyses examined the contribution of SES to heart disease risk independent of baseline Framingham risk score, without and with further adjustment for the ti

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Author

Peter Franks; Paul C Winters; Daniel J Tancredi; Kevin A Fiscella

Publisher

BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, [2001]-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-2261)

Published

2011

Language

EN

Field

Medicine (Health Sciences)