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Synthesis of Commercial Drugs in Chemistry by Cy Moon is a document available to read on EtoBox.

This document summarizes the syntheses of three commercial drugs: Lyrica (pregabalin), Prilosec-Nexium (omeprazole-esomeprazole), and an unnamed drug. For Lyrica, it describes using Evans diastereoselective alkylation to achieve asymmetric synthesis in a very powerful way. For Prilosec-Nexium, it outlines the first synthesis by preparing the compound in racemic form. For the unnamed drug, it provides the starting materials and reaction steps to synthesize the final product.

Author
Cy Moon
Language
EN