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Can I read Discontinuation of Alpha-blocker Therapy in Men with Lower Urinary Tract Symptoms: a Systematic Review and Meta-analysis on EtoBox?
Discontinuation of Alpha-blocker Therapy in Men with Lower Urinary Tract Symptoms: a Systematic Review and Meta-analysis by Henk van der Worp; Petra Jellema; Ilse Hordijk; Yvonne Lisman-van Leeuwen; Lisa Korteschiel; Martijn G Steffens; Marco H Blanker is a Medicine article available to read on EtoBox.
What is Discontinuation of Alpha-blocker Therapy in Men with Lower Urinary Tract Symptoms: a Systematic Review and Meta-analysis about?
## Objectives: We aimed to synthesise the available data for the effect of stopping alpha-blocker therapy among men with lower urinary tract symptoms. the focus was on symptom, uroflowmetry and quality of life outcomes, but we also reviewed the adverse events (aes) and the number of patients who restarted therapy. ## Data sources: We searched medline/pubmed, embase/ovid and the cochrane central register of controlled trials from inception to may 2018. ## Eligibility criteria: We selected studies regardless of study design in which men were treated with an alpha-blocker for at least 3 months and in which the effects of alpha-blocker discontinuation were subsequently studied. only controlled trials were used for the primary objective. ## Data extraction and synthesis: Two reviewers independently extracted data and assessed the risk of bias for the controlled studies only using the cochrane collaboration's tool for assessing risk of bias. data were pooled using random-effects meta-analyses. ## Results: We identified 10 studies (1081 participants) assessing the primary objective. six studies (733 participants) assessed differences in aes between continuation and discontinuation, and si
Who reads Discontinuation of Alpha-blocker Therapy in Men with Lower Urinary Tract Symptoms: a Systematic Review and Meta-analysis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Henk van der Worp; Petra Jellema; Ilse Hordijk; Yvonne Lisman-van Leeuwen; Lisa Korteschiel; Martijn G Steffens; Marco H Blanker
- Published
- 2019
- Language
- EN
- Field
- Medicine (Health Sciences)