About this document
Henderson Approximation by o.n.kozlovska is a document available to read on EtoBox.
The Henderson-Hasselbalch formula provides a method to approximate the pH of buffer solutions using the equation pKa = pH - log10([A-]/[HA]). This approximation simplifies complex calculations for weak acids and bases, although it has limitations regarding the concentration of buffers and the presence of strong acids or bases. The formula was developed by Lawrence Joseph Henderson and modified by Karl Albert Hasselbalch, focusing on equilibrium reactions in biological systems.
- Author
- o.n.kozlovska
- Language
- EN