About this Medicine article

Treatment of Unexplained Chronic Cough: CHEST Guideline and Expert Panel Report by Peter Gibson; Gang Wang; Lorcan McGarvey; Anne E. Vertigan; Kenneth W. Altman; Surinder S. Birring; Todd M. Adams; Kenneth W. Altman; Alan F. Barker; Surinder S. Birring; Fiona Blackhall; Donald C. Bolser; Louis-Philippe Boulet; Sidney S. Braman; Christopher Brightling; Priscilla Callahan-Lyon; Brendan J. Canning; Anne B. Chang; Remy Coeytaux; Terrie Cowley; Paul Davenport; Rebecca L. Diekemper; Satoru Ebihara; Ali A. El Solh; Patricio Escalante; Anthony Feinstein; Stephen K. Field; Dina Fisher; Cynthia T. French; Peter Gibson; Philip Gold; Michael K. Gould; Cameron Grant; Susan M. Harding; Anthony Harnden; Adam T. Hill; Richard S. Irwin; Peter J. Kahrilas; Karina A. Keogh; Andrew P. Lane; Kaiser Lim; Mark A. Malesker; Peter Mazzone; Stuart Mazzone; Douglas C. McCrory; Lorcan McGarvey; Alex Molasiotis; M. Hassan Murad; Peter Newcombe; Huong Q. Nguyen; John Oppenheimer; David Prezant; Tamara Pringsheim; Marcos I. Restrepo; Mark Rosen; Bruce Rubin; Jay H. Ryu; Jaclyn Smith; Susan M. Tarlo; Anne E. Vertigan; Gang Wang; Miles Weinberger; Kelly Weir; Renda Soylemez Wiener is a Medicine article available to read on EtoBox.

## Background: Unexplained chronic cough (ucc) causes significant impairments in quality of life. effective assessment and treatment approaches are needed for ucc. ## Methods: This systematic review of randomized controlled trials (rcts) asked: what is the efficacy of treatment compared with usual care for cough severity, cough frequency, and cough-related quality of life in patients with ucc? studies of adults and adolescents aged > 12 years with a chronic cough of > 8 weeks' duration that was unexplained after systematic investigation and treatment were included and assessed for relevance and quality. based on the systematic review, guideline suggestions were developed and voted on by using the american college of chest physicians organization methodology. ## Results: Eleven rcts and five systematic reviews were included. the 11 rcts reported data on 570 participants with chronic cough who received a variety of interventions. study quality was high in 10 rcts. the studies used an assortment of descriptors and assessments to identify ucc. although gabapentin and morphine exhibited positive effects on cough-related quality of life, only gabapentin was supported as a treatment recom

Author

Peter Gibson; Gang Wang; Lorcan McGarvey; Anne E. Vertigan; Kenneth W. Altman; Surinder S. Birring; Todd M. Adams; Kenneth W. Altman; Alan F. Barker; Surinder S. Birring; Fiona Blackhall; Donald C. Bolser; Louis-Philippe Boulet; Sidney S. Braman; Christopher Brightling; Priscilla Callahan-Lyon; Brendan J. Canning; Anne B. Chang; Remy Coeytaux; Terrie Cowley; Paul Davenport; Rebecca L. Diekemper; Satoru Ebihara; Ali A. El Solh; Patricio Escalante; Anthony Feinstein; Stephen K. Field; Dina Fisher; Cynthia T. French; Peter Gibson; Philip Gold; Michael K. Gould; Cameron Grant; Susan M. Harding; Anthony Harnden; Adam T. Hill; Richard S. Irwin; Peter J. Kahrilas; Karina A. Keogh; Andrew P. Lane; Kaiser Lim; Mark A. Malesker; Peter Mazzone; Stuart Mazzone; Douglas C. McCrory; Lorcan McGarvey; Alex Molasiotis; M. Hassan Murad; Peter Newcombe; Huong Q. Nguyen; John Oppenheimer; David Prezant; Tamara Pringsheim; Marcos I. Restrepo; Mark Rosen; Bruce Rubin; Jay H. Ryu; Jaclyn Smith; Susan M. Tarlo; Anne E. Vertigan; Gang Wang; Miles Weinberger; Kelly Weir; Renda Soylemez Wiener

Published

2015

Language

EN

Field

Medicine (Health Sciences)