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International reproducibility of single breathhold T2\* MR for cardiac and liver iron assessment among five thalassemia centers by Paul Kirk; Taigang He; Lisa J. Anderson; Michael Roughton; Mark A. Tanner; Wynnie W.M. Lam; Wing Y. Au; Winnie C.W. Chu; Godfrey Chan; Renzo Galanello; Gildo Matta; Mark Fogel; Alan R. Cohen; Ru San Tan; Kevin Chen; Ivy Ng; Angie Lai; Suthat Fucharoen; Jiraporn Laothamata; Suporn Chuncharunee; Sutipong Jongjirasiri; David N. Firmin; Gillian C. Smith; Dudley J. Pennell is a Medicine article available to read on EtoBox.

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## Abstract ## Purpose: To examine the reproducibility of the single breathhold T2\* technique from different scanners, after installation of standard methodology in five international centers. ## Materials and Methods: Up to 10 patients from each center were scanned twice locally for local interstudy reproducibility of heart and liver T2\*, and then flown to a central MR facility to be rescanned on a reference scanner for intercenter reproducibility. Interobserver reproducibility for all scans was also assessed. ## Results: Of the 49 patients scanned, the intercenter reproducibility for T2\* was 5.9% for the heart and 5.8% for the liver. Local interstudy reproducibility for T2\* was 7.4% for the heart and 4.6% for the liver. Interobserver reproducibility for T2\* was 5.4% for the heart and 4.4% for the liver. ## Conclusion: These data indicate that T2\* MR may be developed into a widespread test for tissue siderosis providing that well‐defined and approved imaging and analysis techniques are used. J. Magn. Reson. Imaging 2010;32:315–319. © 2010 Wiley‐Liss, Inc.

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Author

Paul Kirk; Taigang He; Lisa J. Anderson; Michael Roughton; Mark A. Tanner; Wynnie W.M. Lam; Wing Y. Au; Winnie C.W. Chu; Godfrey Chan; Renzo Galanello; Gildo Matta; Mark Fogel; Alan R. Cohen; Ru San Tan; Kevin Chen; Ivy Ng; Angie Lai; Suthat Fucharoen; Jiraporn Laothamata; Suporn Chuncharunee; Sutipong Jongjirasiri; David N. Firmin; Gillian C. Smith; Dudley J. Pennell

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-1807)

Published

2010

Language

EN

Field

Medicine (Health Sciences)