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Direct Patterning of Anti-Human Serum Albumin Antibodies on Aldehyde-Terminated Silicon Nitride Surfaces for HSA Protein Detection by David Caballero; Josep Samitier; Joan Bausells; Abdelhamid Errachid is a Engineering article available to read on EtoBox.

What is Direct Patterning of Anti-Human Serum Albumin Antibodies on Aldehyde-Terminated Silicon Nitride Surfaces for HSA Protein Detection about?

In the field of biosensors, the development of adequate biochemical-modified surfaces is of crucial importance. [1][2][3][4] Considerable effort is put into the development of such substrates in order to achieve highly sensitive and selective detection and analysis of biorecognition processes. [5,6] Recently advances include proposed procedures for the immobilization of biomolecules (antibodies, DNA, peptides, etc.). [7][8][9][10] The deposition and immobilization of such biological recognition layers is crucial for the performance of biosensors. [11] I ́n particular, special care has to be taken as non-fixed biomolecules may be removed during stringent washing. Thus, a robust covalent attachment method is desired. For electrochemical biosensors, the key point is the integration of the biological elements with suitable materials; and much work is still required in this area. [12,13] Different immunosensors based on an electrolyteinsulator-semiconductor (EIS) structure have been developed in which the attachment of the antigen to the corresponding antibody triggers an electric response in the sensor. [14,15] For immunosensing applications, a fast-to-functionalize and efficient proc

Who reads Direct Patterning of Anti-Human Serum Albumin Antibodies on Aldehyde-Terminated Silicon Nitride Surfaces for HSA Protein Detection?

Author

David Caballero; Josep Samitier; Joan Bausells; Abdelhamid Errachid

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); Wiley - V C H Verlag GmbbH & Co.; Publons; Wiley (ISSN 1613-6810)

Published

2009

Language

EN

Field

Engineering (Physical Sciences)