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In vivo evaluation of a collagen membrane in bone neoformation: A morphological and histomorphometric study by Marcello Kfouri Di Pillo; Pedro Giorgetti Montagner; Lucas Novaes Teixeira; Elizabeth Ferreira Martinez is a Medicine article available to read on EtoBox.

What is In vivo evaluation of a collagen membrane in bone neoformation: A morphological and histomorphometric study about?

Objective Guided bone regeneration (GBR) is a technique that involves the placement of mechanical barriers to protect the blood clot, and create an isolated space to prevent competition from epithelial and connective tissues in bone augmentation treatments. Collagen membranes stand out from other materials available for performing regenerative surgeries, and are widely used because of their ability to promote cell adhesion and homeostasis, and their biocompatibility, ease of handling, and low immunogenicity. In this context, researchers have investigated xenogenic membranes/barriers that cost less and have slower resorption rates. The current study aimed to assess the osteogenic potential induced by a crosslinked, synthesized xenogenic membrane 100 μm thick when applied in vivo to critical defects in rat calvaria. Material and methods Critical size defects were created in the calvaria of thirty male Wistar rats, and randomly divided into the following two groups: G1 – clot covered with a commercial xenogenic membrane (Lumina-Coat®, Criteria, Brazil), and G2 – clot covered with a synthesized xenogenic membrane. The animals were euthanized after 7, 15 and 30 days, and samples of calv

Who reads In vivo evaluation of a collagen membrane in bone neoformation: A morphological and histomorphometric study?

Author

Marcello Kfouri Di Pillo; Pedro Giorgetti Montagner; Lucas Novaes Teixeira; Elizabeth Ferreira Martinez

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)