About this Agricultural and Biological Sciences article
Progressive and regressive infection with feline leukemia virus (FeLV) in cats in southern Brazil: Prevalence, risk factors associated, clinical and hematologic alterations by Giovana Biezus; Thierry Grima de Cristo; Mariana da Silva Casa; Mariângela Lovatel; Mayara Vavassori; Marcela Brüggemann de Souza Teixeira; Luiz Claudio Miletti; Ubirajara Maciel da Costa; Renata Assis Casagrande is a Agricultural and Biological Sciences article available to read on EtoBox.
Enzyme-linked immunosorbent assay (ELISA) for viral antigen is commonly used for the diagnosis of progressive feline leukemia virus (FeLV) infection but is not able to determine the true prevalence of infection when used as the sole test. Additional testing to detect proviral DNA will identify regressive (antigen negative) FeLV infections as well as progressive infections. Therefore, this study aimed to determine the prevalence of progressive and regressive FeLV infection, outcome-associated factors, and hematologic changes. A cross-sectional study was performed on 384 cats selected from routine hospital care. Blood samples were subjected to complete blood count, ELISA for FeLV antigen and FIV antibody, and nested PCR amplifying the U3-LTR region and gag gene, which are conserved in most exogenous FeLV. The prevalence of FeLV infection was 45.6% (CI 95% 40.6-50.6%). The prevalence of progressive infection (FeLV + P) was 34.4% (CI 95% 29.6-39.1%), that of regressive infection (FeLV+R) was 10.4% (CI 95% 7.4-13.4%), for discordant but positive results 0.8% (CI 95% 0.75-0.84%), for FeLV + P coinfected with FIV 2.6% (CI 95% 1.2-4.0%), and FeLV + R coinfected with FIV 1.5% (CI 95% 0.3-2.
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- Author
- Giovana Biezus; Thierry Grima de Cristo; Mariana da Silva Casa; Mariângela Lovatel; Mayara Vavassori; Marcela Brüggemann de Souza Teixeira; Luiz Claudio Miletti; Ubirajara Maciel da Costa; Renata Assis Casagrande
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)