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Causes of the zonal distribution of glycogen in the liver acinus after a fat-rich diet. I. Glycogen deposition in the acini of rat livers during "normal" and "reversed" perfusion by W. Den Otter; G. Tuit is a Medicine article available to read on EtoBox.

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Different acinar glycogen patterns are observed in rat liver after different diets. Experiments were carried out to determine if these patterns depend on the concentration of blood glucose in the various zones of the acinus or on the direction of the blood flow. It is possible to investigate this problem by reversal of blood flow in a perfusion apparatus. Livers were perfused with Krebs-Henseleit solution, the same volume of bovine erythrocytes, and 379 mg% glucose, 2.5% albumin and different quantities of heparin. Perfusion in the normal direction is possible through the vena porta and in the reversed direction by perfusing through the vena cava. The reported results show that glycogen localization depends on the acinar enzyme pattern for glycogen synthesis rather than the direction of blood flow.

Who reads Causes of the zonal distribution of glycogen in the liver acinus after a fat-rich diet. I. Glycogen deposition in the acini of rat livers during "normal" and "reversed" perfusion?

Author

W. Den Otter; G. Tuit

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0003-276X)

Published

1972

Language

EN

Field

Medicine (Health Sciences)