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What is Abcb1: Expert Opinion On Drug Safety about?

This systematic review and meta-analysis investigates the impact of the ABCB1 C3435T genetic polymorphism on major adverse cardiovascular events (MACE) in patients with acute coronary syndrome or coronary artery disease undergoing percutaneous coronary intervention while treated with clopidogrel. The findings indicate that the homozygous mutant genotype (TT) is associated with a significantly increased risk of MACE compared to wild type genotypes, while safety outcomes related to bleeding events were not si

Author

SARA GOMEZ TRIANA

Language

EN