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S Albendazole Immune-mediated toxic hepatitis: case report An 8-year-old girl developed immune-mediated toxic hepatitis following treatment with albendazole for Enterobius vermicularis infection [route and dosage not sated; duration of treatment to reaction onset not clearly stated].The girl was diagnosed with Enterobius vermicularis infection following a stool sample investigation. She started receiving albendazole. However, after the third dose of albendazole, she experienced nausea, vomiting and fever.Albendazole was discontinued. Thereafter, the girl's symptoms ceased. Fifteen days after stopping albendazole, she started receiving mebendazole for intestinal parasitosis. On the third day of mebendazole therapy, she experienced abdominal pain, nausea and dark urine. Laboratory analyses revealed increased level of transaminases and parameters of cholestasis. Immunological analyses revealed significantly increased IgG levels. She started receiving treatment with prednisolone and ursodeoxycholic acid. Based on the RUCAM score of 8, mixed liver injury, most likely due to drug induced liver injury was initially suspected. Histopathological findings after a percutaneous liver biopsy sh

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Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Medicine (Health Sciences)