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Can I read Needle‐free cervical cancer treatment using helical multishield intracavitary rotating shield brachytherapy with the ^169^Yb Isotope on EtoBox?
Needle‐free cervical cancer treatment using helical multishield intracavitary rotating shield brachytherapy with the ^169^Yb Isotope by Karolyn M. Hopfensperger; Quentin Adams; Yusung Kim; Xiaodong Wu; Weiyu Xu; Kaustubh Patwardhan; Bounnak Thammavong; Joseph Caster; Ryan T. Flynn is a Medicine article available to read on EtoBox.
What is Needle‐free cervical cancer treatment using helical multishield intracavitary rotating shield brachytherapy with the ^169^Yb Isotope about?
## Purpose To assess the capability of an intracavitary ^169^Yb‐based helical multishield rotating shield brachytherapy (RSBT) delivery system to treat cervical cancer. The proposed RSBT delivery system contains a pair of 1.25 mm thick platinum partial shields with 45° and 180° emission angles, which travel in a helical pattern within the applicator. ## Methods A helically threaded tandem applicator with a 45° tandem curvature containing a helically threaded catheter was designed. A 0.6 mm diameter ^169^Yb source with a length of 10.5 mm was simulated. A 37‐patient treatment planning study, based on Monte Carlo dose calculations using MCNP5, was conducted with high‐risk clinical target volumes (HR‐CTVs) of 41.2–192.8 cm^3^ (average ± standard deviation of 79.9 ± 35.8 cm^3^). All patients were assumed to receive 25 fractions of 1.8 Gy of external beam radiation therapy (EBRT) before receiving 5 fractions of high‐dose‐rate brachytherapy (HDR‐BT). For each patient, ^192^Ir‐based intracavitary (IC) HDR‐BT, ^192^Ir‐based intracavitary/interstitial (IC/IS) HDR‐BT using a hybrid applicator with eight IS needles, and ^169^Yb‐based RSBT plans were generated. ## Results For the IC, IC/IS, an
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- Author
- Karolyn M. Hopfensperger; Quentin Adams; Yusung Kim; Xiaodong Wu; Weiyu Xu; Kaustubh Patwardhan; Bounnak Thammavong; Joseph Caster; Ryan T. Flynn
- Publisher
- American Institute of Physics; Wiley (John Wiley & Sons); John Wiley and Sons Inc.; Wiley; Research Square (ISSN 0094-2405)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)