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This study presents a method for the simultaneous spectrochromatographic determination of dorzolamide hydrochloride and timolol maleate in an ophthalmic solution using three-way analysis methods, specifically parallel factor analysis (PARAFAC) and three-way partial least squares (3W-PLS). The analysis successfully quantifies the compounds in the presence of an internal standard, demonstrating comparable results to traditional UPLC methods. The research highlights the advantages of multiway resolution techni

Author

phtvietrsdlg1

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EN