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This document summarizes several nonmalignant leukocyte disorders including: 1) Pelger-Huet anomaly, which is caused by a mutation in the lamin B-receptor gene and results in abnormal nuclear segmentation of leukocytes. Pseudo-PHA can also be seen in infections and hematologic malignancies. 2) Neutrophil hypersegmentation is associated with megaloblastic anemias and myelodysplastic syndromes. 3) Chronic granulomatous disease is an inherited disorder causing decreased ability of phagocytes to produce re

Author

Kerstine Sotto

Language

EN