About this document
Ovarian Cancer Risk in BRCA Negative Families by Fitria Dewinur is a document available to read on EtoBox.
This study examined the risk of ovarian cancer in 8005 women from 895 families seen at a family history clinic in Manchester, UK. The study found that women from families with BRCA2 mutations had a 17-fold increased risk of invasive ovarian cancer, while those from BRCA1 mutation families had a 50-fold increased risk. However, the study found no association between ovarian cancer risk and families that tested negative for BRCA1/2 mutations, with only 1 observed case of invasive ovarian cancer versus the exp
- Author
- Fitria Dewinur
- Language
- EN