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ABC Transporters and Multidrug Resistance by Boumendjel, Ahcne; Boutonnat, Jean; Robert, Jacques is a scholarly article available to read on EtoBox.

What is ABC Transporters and Multidrug Resistance about?

A comprehensive review of the most current scientific research on ABC transporters and multidrug resistance ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventually develop resistance to not only the drug they are taking, but to several different types of drugs. ABC Transporters and Multidrug Resistance offers an essential resource for pharmaceutical researchers who are working to discover drugs to counteract multidrug resistance in diseases such as cancer. In one comprehensive volume, this book contains a collection of the most current knowledge on the involvement of ABC transporters in drug transport and resistance. This comprehensive volume provides an overview on the description of the structure, the genome, normal tissue expression, physiological aspect, and mechanism of action of the ABC protein. The expert contributors explore the expression, detection, and implications of ABC proteins in hematological malignancies and soli

Author

Boumendjel, Ahcne; Boutonnat, Jean; Robert, Jacques

Publisher

John Wiley & Sons, Incorporated

Published

2009

Language

EN

ISBN

9780470495131