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What is Procyanidin C1 about?
The study demonstrates that procyanidin C1 (PCC1), a flavonoid from grape seed extract, exhibits senotherapeutic properties that enhance lifespan and healthspan in mice by targeting senescent cells. PCC1 inhibits the senescence-associated secretory phenotype (SASP) at low concentrations and selectively kills senescent cells at higher concentrations, potentially improving chemotherapy outcomes. This research identifies PCC1 as a promising natural senolytic agent with significant potential for clinical applic
- Author
- sharenskie
- Language
- EN