Can I read Cost-effectiveness of preoperative radiotherapy in rectal cancer: results from the Swedish Rectal Cancer Trial on EtoBox?

Cost-effectiveness of preoperative radiotherapy in rectal cancer: results from the Swedish Rectal Cancer Trial by Michael Dahlberg; Anna Stenborg; Lars Påhlman; Bengt Glimelius is a Medicine article available to read on EtoBox.

What is Cost-effectiveness of preoperative radiotherapy in rectal cancer: results from the Swedish Rectal Cancer Trial about?

## Purpose: The swedish rectal cancer trial (srct) demonstrated that a short-term regimen of high-dose fractionated preoperative radiotherapy (5 x 5 gy) reduced the local recurrence rates and improved overall survival. this has had an impact on the primary treatment of rectal cancer. the current study investigated the cost-effectiveness of the new combined approach. ## Methods and materials: After an 8-year follow-up, in-hospital and outpatient costs related to the treatment of rectal cancer and its complications were analyzed for 98 randomly allocated patients who participated in the srct from a single swedish health care region. the costs were then related to the clinical data from the srct regarding complications, local and distant recurrences, and survival. ## Results: The total cost for a nonirradiated patient was us$30,080 compared with us$35,268 for an irradiated patient. the surgery-alone group had increased costs related to local recurrences, and the radiotherapy group had increased costs for irradiation and complications. with a survival benefit of 21 months (retrieved from the srct), the cost for a saved year was us$3654. sensitivity analyses for different rates of local

Who reads Cost-effectiveness of preoperative radiotherapy in rectal cancer: results from the Swedish Rectal Cancer Trial?

Author

Michael Dahlberg; Anna Stenborg; Lars Påhlman; Bengt Glimelius

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2002

Language

EN

Field

Medicine (Health Sciences)