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Cao et al. developed a high-yielding fed-batch process for producing porcine circovirus type 2 virus-like particles (PCV2-VLPs) using Sf9 cells, optimizing feeding strategies and cell density to enhance production. The final yields reached 110 mg/L, significantly improving upon traditional batch culture methods. This efficient production process offers a promising approach for the industrial manufacture of PCV2 subunit vaccines.

Author

Lorena Boado

Language

EN