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In Oculo Transplants of Myometrium from Postpartum Guinea Pigs Fail to Support Sympathetic Reinnervation by M. MONICA BRAUER; GEOFFREY BURNSTOCK; CHRISTOPHER THRASIVOULOU; TIMOTHY COWEN is a Earth and Planetary Sciences article available to read on EtoBox.

What is In Oculo Transplants of Myometrium from Postpartum Guinea Pigs Fail to Support Sympathetic Reinnervation about?

Sympathetic nerves to the enlarged fetus‐containing region of the uterus undergo degenerative changes during late pregnancy and show slow regrowth after parturition. It is not known whether this unusual response of sympathetic nerves to smooth muscle hypertrophy is due to the sensitivity of short adrenergic neurons to hormonal changes, or whether the nerves respond to changes in the neurotrophic capacity of the target. We have investigated this question using in oculo transplantation. Small pieces of myometrium from the uterine horn of virgin guinea pigs, or from the region previously occupied by the placenta and fetus in postpartum guinea pigs, were transplanted into the anterior eye chamber. After 3 wk in oculo, the pattern of reinnervation of the transplants was assessed on whole mount stretch preparations stained for tyrosine hydroxylase. The histology of the transplants was examined in toluidine blue‐stained semithin sections. Myometrial transplants from virgin donors and uterine artery transplants from both virgin and postpartum donors became organotypically reinnervated by sympathetic fibres from the host iris. In contrast, sympathetic nerves did not reinnervate myometrial t

Who reads In Oculo Transplants of Myometrium from Postpartum Guinea Pigs Fail to Support Sympathetic Reinnervation?

Author

M. MONICA BRAUER; GEOFFREY BURNSTOCK; CHRISTOPHER THRASIVOULOU; TIMOTHY COWEN

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0021-8782)

Published

1998

Language

EN

Field

Earth and Planetary Sciences (Physical Sciences)