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What is Internal Standard and Standard Addition Methods about?

Internal standard is a known compound added to samples that is used to quantify an analyte. The signal from the analyte is compared to the signal from the internal standard. This allows the determination of a response factor used to calculate the concentration of an analyte in an unknown sample based on its peak area and the peak area and known concentration of the internal standard. Standard addition involves adding known concentrations of an analyte to a sample to determine the original unknown concentrat

Author
Moh Hari Rusli
Language
EN

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