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Can I read Pursuing the Voltage Sensor of a Voltage-gated Mammalian Potassium Channel. on EtoBox?
Pursuing the Voltage Sensor of a Voltage-gated Mammalian Potassium Channel. by J Tytgat; K Nakazawa; A Gross; P Hess is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Pursuing the Voltage Sensor of a Voltage-gated Mammalian Potassium Channel. about?
Ion channels are generally classified as voltage- or ligand-gated channels based upon their ability to respond to a change in the transmembrane voltage or to a specific ligand interaction. The voltage sensor of voltage-gated ion channels is thought to be contained within the fourth putative transmembrane segment, S4, and is characterized by basic residues typically spaced apart. Thus far, a full understanding of all charges contributing to the voltage sensor of voltage-gated potassium channels has been lacking since several neutralization mutants in S4 could not be functionally expressed. By construction of multimeric cDNAs encoding a mammalian RCK1 (Kv1.1) potassium channel, we now report functional expression of all charge neutralizations in the S4 segment, providing a more comprehensive insight into the functioning of the voltage sensor.
Who reads Pursuing the Voltage Sensor of a Voltage-gated Mammalian Potassium Channel.?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- J Tytgat; K Nakazawa; A Gross; P Hess
- Publisher
- Elsevier BV
- Published
- 1993
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)