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This document discusses five cases of FIGO grade 3 uterine endometrioid adenocarcinomas (UECs) exhibiting aggressive behavior and morphologic resemblance to cutaneous pilomatrix carcinomas, characterized by aberrant ß-catenin expression. All tumors showed high-grade features, with significant clinical aggressiveness, as three out of four patients with follow-up died within 14 months of diagnosis. Molecular analysis revealed CTNNB1 mutations in two cases, highlighting the need for awareness of this aggressiv
- Author
- Shashank
- Language
- EN