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What is Cre-loxP Technology in Mouse Models about?

The laboratory mouse is a valuable model for studying human diseases due to its physiological similarity and manipulable genome, particularly with the advent of Cre-loxP technology that allows for conditional mutations. This technology enables researchers to create specific genetic alterations in a controlled manner, leading to three possible outcomes: excision, inversion, or translocation of genetic sequences. Additionally, Cre reporter strains help confirm the activity of Cre recombinase in specific tissu

Author

waelosmzan2000

Language

EN