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Efficacy and safety of systemic recombinant interferon-alpha in Behcet's disease by Georgiou; Monastirli; Pasmatzi; Gartaganis; Goerz; Tsambaos is a Medicine article available to read on EtoBox.

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Georgiou S, Monastirli A, Pasmatzi E, Gartaganis S, Goerz G, Tsambaos D (Departments of Dermatology and Ophthalmology, University of Patras, Greece and the Department of Dermatology, Heinrich‐Heine University of Düsseldorf, Germany). Efficacy and safety of systemic recombinant interferon‐alpha in Behcet's disease. __J Intern Med__ 1998; 243: 367–72. ## Objectives To evaluate the therapeutic efficacy and safety of systemic recombinant interferon α‐2a (IFN ‐α) in patients with Behcet's disease (BD) and to determine the incidence of episodes in complete responders during the one‐year pretreatment period and follow‐up. ## Design An open clinical study. ## Setting Departments of Dermatology and Ophthalmology, University of Patras, Greece and Department of Dermatology, Heinrich‐Heine University of Düsseldorf, Germany. ## Subjects Twelve patients (aged 23–52 years) with active BD who had previously been unsuccessfully treated with systemic steroids and/or immunosuppressives. ## Interventions IFN‐α was administered subcutaneously at a dose of 6 × 10^6^ IU per day 3 times per week for 2 months. ## Main outcome measures Change of area or number of mucocutaneous lesions, grading score for thr

Who reads Efficacy and safety of systemic recombinant interferon-alpha in Behcet's disease?

Author

Georgiou; Monastirli; Pasmatzi; Gartaganis; Goerz; Tsambaos

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0954-6820)

Published

1998

Language

EN

Field

Medicine (Health Sciences)