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Preserving female fertility following cancer treatment: Current options and future possibilities by Erin R. West; Mary B. Zelinski; Laxmi A. Kondapalli; Clarisa Gracia; Jeffrey Chang; Christos Coutifaris; John Critser; Richard L. Stouffer; Lonnie D. Shea; Teresa K. Woodruff is a Medicine article available to read on EtoBox.

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## Abstract Children and women of reproductive age are increasingly surviving cancer diagnoses, and therefore long‐term quality‐of‐life issues are of greater importance at the time of diagnosis. Cancer therapies including radiation and chemotherapy can be detrimental to fertility, and therefore many patients are motivated to preserve fertility prior to cancer treatment. The only highly successful method in preserving fertility to date is embryo cryopreservation, which may not be appropriate for some patients due to age, delay in treatment, cancer type and stage, as well as availability of an acceptable sperm donor. Alternative methods including oocyte cryopreservation and ovarian tissue banking may also preserve fertility while providing additional flexibility to patients. In vitro ovarian follicle maturation following tissue banking is one potential approach that would not require a delay in cancer therapy for ovarian stimulation, would not require an immediate sperm donor, and does not carry the risk of reintroducing malignant cells following tissue transplantation. In vitro follicle culture systems have resulted in successful live births in the mouse. However, many challenges mu

Who reads Preserving female fertility following cancer treatment: Current options and future possibilities?

Author

Erin R. West; Mary B. Zelinski; Laxmi A. Kondapalli; Clarisa Gracia; Jeffrey Chang; Christos Coutifaris; John Critser; Richard L. Stouffer; Lonnie D. Shea; Teresa K. Woodruff

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1545-5009)

Published

2009

Language

EN

Field

Medicine (Health Sciences)