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Surveillance and Molecular Characterization of Rotavirus Strains Circulating in Odisha, India after Introduction of Rotavac by Vishwanath Ghoshal; Manas Kumar Nayak; Namrata Misra; Ranjith Kumar; Samarasimha Reddy N; Nirmal Kumar Mohakud is a scholarly article available to read on EtoBox.

What is Surveillance and Molecular Characterization of Rotavirus Strains Circulating in Odisha, India after Introduction of Rotavac about?

## Objective: To know the rotavirus burden associated with acute gastroenteritis along with circulating genotypes among under-five children and to find out possible associations with different demographic and clinical predictors in a tertiary care teaching hospital in bhubaneswar, odisha. ## Methods: A prospective acute gastroenteritis surveillance conducted from february 2016 to june 2019 at a tertiary care pediatric hospital in bhubaneswar has enrolled 850 children under five years of age. the stool samples were tested for vp6 antigen of rotavirus by enzyme immunoassay (eia) and hemi-nested multiplex pcr to find out vp7 (g type) and vp4 (p type) genes. the data was presented using mean ± sd, median (iqr) along with frequencies and percentages. ## Results: Rotavirus positivity was found in 246 children (28.9%) with male: female ratio of 3:1. an increasing trend of rotaviral diarrheal cases was seen during the winter months. history of vomiting for 2 d, age group of 12-23 mo, and fever were significantly associated with rotavirus diarrhea having odd ratios of 1.80 (95% ci, 1.48, and 1.69, respectively). among the genotypes, g3 and p8 were found to be most common in the present stud

Author

Vishwanath Ghoshal; Manas Kumar Nayak; Namrata Misra; Ranjith Kumar; Samarasimha Reddy N; Nirmal Kumar Mohakud

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN