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The citric acid cycle, also known as the Krebs cycle or TCA cycle, is a series of mitochondrial reactions that catabolize acetyl-CoA into CO2 and H2O while generating ATP. It operates under aerobic conditions and is regulated by the energy status of the cell, with key enzymes being citrate synthase, isocitrate dehydrogenase, and α-ketoglutarate dehydrogenase. The cycle plays a significant role in energy production and serves as a metabolic hub for carbohydrates, lipids, and proteins.

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adilkarzan249

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